2012
Objective 1: Construction of ionic thin filmsby the layer-by-layer deposition technique and the evaluation of sorption/immobilization potential for some bioactive compounds, using ionic or ionizable synthetic or natural polymers
Objective 2: Design of new porous ionic multifunctional (PIM) hydrogels based on poly(acrylamide and natural ionic polymers through by cryogelifiation technique (IPN type ionic cryogels)
2013
Objective 1: synthesis of novel "smart" ionic porous matrices multiple-responsive to external stimuli, based on poly(acrylamide) as a matrix and poly(N,N-dimethylaminoethyl methacrilate) (PDMAEM), polymer responsive to pH and temperature, as entrapped polymer, for the immobilization/release of bioactive compounds.
Task 1: Synthesis and characterization of PDMAEM with different molar masses and charge densities
Task 2: Synthesis of the new multicomponent, super-porous materials below the freezing temperature of the reaction medium
Task 3: Structural and morphological characterization of the IPN-type porous ionic cryogels
Task 4: Studying the swelling kinetics and equilibrium swelling ratio as a function of pH and temperature
Task 5: Controlled immobilization and release studies of some model compounds (dyes, drugs etc.)
2014
Objective 1: Novel porous ionic matrices based on cross-linked PDMAEM as matrix and a water soluble non-ionic polymer as entrapped polymer (PAAm, PVA) obtained by cryogelation technique
Task 1: Synthesis of superporous multicomponent ionic semi-IPN cryogels
Task 2: Structural and morphological characterization of the gels as a function of the synthesis conditions
Task 3: Formation of complexes between the cryogels and some some metal ions
Task 4: Studying the immobilization/releasing efficiency of some model compounds onto/from the novel cryogels, before and after the complexation with ionic metals
2015
Objective 1: Synthesis by cryogelation of some novel “smart” porous ionic matrices (PIM) based on cross-linked PDMAEM as matrix and native or ionic starch as entrapped polymer and evaluation of their efficiency in sorption/releasing of bioactive compounds
Task 1: Synthesis and characterization of starch based polyanions
Task 2: Synthesis and characterization of IPN type cryogels based on cross-linked PDMAEM and native starch or starch based polyanion
Task 3: Evaluation of the response at various external stimuli (pH, Temperature, ionic strength) of the novel composite cryogels
2016
Objective 1: Synthesis by cryogelation of some novel “smart” porous ionic matrices (PIM) based on cross-linked PDMAEM as matrix and native or ionic starch as entrapped polymer and evaluation of their efficiency in sorption/releasing of bioactive compounds
Task 1: Evaluation of possible biomedical applications of the novel porous ionic matrices with fast response to external factors by sorption/release experiments of some model ionic compounds (dyes, drugs, proteins)
Objective 1: Construction of ionic thin filmsby the layer-by-layer deposition technique and the evaluation of sorption/immobilization potential for some bioactive compounds, using ionic or ionizable synthetic or natural polymers
Objective 2: Design of new porous ionic multifunctional (PIM) hydrogels based on poly(acrylamide and natural ionic polymers through by cryogelifiation technique (IPN type ionic cryogels)
2013
Objective 1: synthesis of novel "smart" ionic porous matrices multiple-responsive to external stimuli, based on poly(acrylamide) as a matrix and poly(N,N-dimethylaminoethyl methacrilate) (PDMAEM), polymer responsive to pH and temperature, as entrapped polymer, for the immobilization/release of bioactive compounds.
Task 1: Synthesis and characterization of PDMAEM with different molar masses and charge densities
Task 2: Synthesis of the new multicomponent, super-porous materials below the freezing temperature of the reaction medium
Task 3: Structural and morphological characterization of the IPN-type porous ionic cryogels
Task 4: Studying the swelling kinetics and equilibrium swelling ratio as a function of pH and temperature
Task 5: Controlled immobilization and release studies of some model compounds (dyes, drugs etc.)
2014
Objective 1: Novel porous ionic matrices based on cross-linked PDMAEM as matrix and a water soluble non-ionic polymer as entrapped polymer (PAAm, PVA) obtained by cryogelation technique
Task 1: Synthesis of superporous multicomponent ionic semi-IPN cryogels
Task 2: Structural and morphological characterization of the gels as a function of the synthesis conditions
Task 3: Formation of complexes between the cryogels and some some metal ions
Task 4: Studying the immobilization/releasing efficiency of some model compounds onto/from the novel cryogels, before and after the complexation with ionic metals
2015
Objective 1: Synthesis by cryogelation of some novel “smart” porous ionic matrices (PIM) based on cross-linked PDMAEM as matrix and native or ionic starch as entrapped polymer and evaluation of their efficiency in sorption/releasing of bioactive compounds
Task 1: Synthesis and characterization of starch based polyanions
Task 2: Synthesis and characterization of IPN type cryogels based on cross-linked PDMAEM and native starch or starch based polyanion
Task 3: Evaluation of the response at various external stimuli (pH, Temperature, ionic strength) of the novel composite cryogels
2016
Objective 1: Synthesis by cryogelation of some novel “smart” porous ionic matrices (PIM) based on cross-linked PDMAEM as matrix and native or ionic starch as entrapped polymer and evaluation of their efficiency in sorption/releasing of bioactive compounds
Task 1: Evaluation of possible biomedical applications of the novel porous ionic matrices with fast response to external factors by sorption/release experiments of some model ionic compounds (dyes, drugs, proteins)